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Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoevatromonoside (GEV) out of 46 CGs for its low nanom...
Autores principales: | Schneider, Naira F. Z., Cerella, Claudia, Lee, Jin-Young, Mazumder, Aloran, Kim, Kyung Rok, de Carvalho, Annelise, Munkert, Jennifer, Pádua, Rodrigo M., Kreis, Wolfgang, Kim, Kyu-Won, Christov, Christo, Dicato, Mario, Kim, Hyun-Jung, Han, Byung Woo, Braga, Fernão C., Simões, Cláudia M. O., Diederich, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838923/ https://www.ncbi.nlm.nih.gov/pubmed/29545747 http://dx.doi.org/10.3389/fphar.2018.00070 |
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