Blockade of TIM3 relieves immunosuppression through reducing regulatory T cells in head and neck cancer

BACKGROUND: T-cell immunoglobulin mucin 3 (TIM3) is a negative immune checkpoint and plays a crucial part in tumor-induced immune suppression. However, the mechanism of TIM3 in regulating immunosuppression in head and neck squamous cell carcinoma (HNSCC) was still not quite clear. METHODS: We carrie...

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Detalles Bibliográficos
Autores principales: Liu, Jian-Feng, Wu, Lei, Yang, Lei-Lei, Deng, Wei-Wei, Mao, Liang, Wu, Hao, Zhang, Wen-Feng, Sun, Zhi-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838931/
https://www.ncbi.nlm.nih.gov/pubmed/29506555
http://dx.doi.org/10.1186/s13046-018-0713-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838931/
https://www.ncbi.nlm.nih.gov/pubmed/29506555
http://dx.doi.org/10.1186/s13046-018-0713-7

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