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Correlation between the results of in vitro and in vivo chromosomal damage tests in consideration of exposure levels of test chemicals
INTRODUCTION: We examined the correlation between the results of in vitro and in vivo chromosomal damage tests by using in-house data of 18 pharmaceutical candidates that showed positive results in the in vitro chromosomal aberration or micronucleus test using CHL/IU cells, and quantitatively analyz...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838998/ https://www.ncbi.nlm.nih.gov/pubmed/29556374 http://dx.doi.org/10.1186/s41021-018-0094-3 |