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Effects of dexamethasone on the Li-pilocarpine model of epilepsy: protection against hippocampal inflammation and astrogliosis
BACKGROUND: Temporal lobe epilepsy (TLE) is the most common form of partial epilepsy and is accompanied, in one third of cases, by resistance to antiepileptic drugs (AED). Most AED target neuronal activity modulated by ionic channels, and the steroid sensitivity of these channels has supported the u...
Autores principales: | Vizuete, Adriana Fernanda K., Hansen, Fernanda, Negri, Elisa, Leite, Marina Concli, de Oliveira, Diogo Losch, Gonçalves, Carlos-Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839012/ https://www.ncbi.nlm.nih.gov/pubmed/29506554 http://dx.doi.org/10.1186/s12974-018-1109-5 |
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