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Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial‐Like Cells
Cornea is a clear outermost layer of the eye which enables transmission of light onto the retina. The transparent corneal epithelium is regenerated by limbal stem cells (LSCs), whose loss/dysfunction results in LSCs deficiency (LSCD). Ex vivo expansion of autologous LSCs obtained from patient's...
Autores principales: | Kamarudin, Taty Anna, Bojic, Sanja, Collin, Joseph, Yu, Min, Alharthi, Sameer, Buck, Harley, Shortt, Alex, Armstrong, Lyle, Figueiredo, Francisco C., Lako, Majlinda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839253/ https://www.ncbi.nlm.nih.gov/pubmed/29226476 http://dx.doi.org/10.1002/stem.2750 |
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