The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer

Medical practitioners are recommending combination therapy in cancer for its various advantages. Combination therapy increases the efficacy of treatment due to its synergistic effects in cancer treatment. In this post-genomic era, microRNAs (miRNAs) are receiving attention for their role in human di...

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Autores principales: Chakraborty, Chiranjib, Sharma, Ashish Ranjan, Sharma, Garima, Sarkar, Bimal Kumar, Lee, Sang-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839381/
https://www.ncbi.nlm.nih.gov/pubmed/29515800
http://dx.doi.org/10.18632/oncotarget.24309
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author Chakraborty, Chiranjib
Sharma, Ashish Ranjan
Sharma, Garima
Sarkar, Bimal Kumar
Lee, Sang-Soo
author_facet Chakraborty, Chiranjib
Sharma, Ashish Ranjan
Sharma, Garima
Sarkar, Bimal Kumar
Lee, Sang-Soo
author_sort Chakraborty, Chiranjib
collection PubMed
description Medical practitioners are recommending combination therapy in cancer for its various advantages. Combination therapy increases the efficacy of treatment due to its synergistic effects in cancer treatment. In this post-genomic era, microRNAs (miRNAs) are receiving attention for their role in human disease and disease therapy. In this review, we discuss the combination of miRNAs and chemotherapeutic agents for cancer treatment. Moreover, we attempted to portray the role of miRNAs in cancer therapy; outline combination therapy, especially chemo-combination therapy, and discuss the basis for miRNA-based chemo-combination therapies and chemo-combination therapy with miRNA for cancer treatment.
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spelling pubmed-58393812018-03-07 The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer Chakraborty, Chiranjib Sharma, Ashish Ranjan Sharma, Garima Sarkar, Bimal Kumar Lee, Sang-Soo Oncotarget Review Medical practitioners are recommending combination therapy in cancer for its various advantages. Combination therapy increases the efficacy of treatment due to its synergistic effects in cancer treatment. In this post-genomic era, microRNAs (miRNAs) are receiving attention for their role in human disease and disease therapy. In this review, we discuss the combination of miRNAs and chemotherapeutic agents for cancer treatment. Moreover, we attempted to portray the role of miRNAs in cancer therapy; outline combination therapy, especially chemo-combination therapy, and discuss the basis for miRNA-based chemo-combination therapies and chemo-combination therapy with miRNA for cancer treatment. Impact Journals LLC 2018-01-23 /pmc/articles/PMC5839381/ /pubmed/29515800 http://dx.doi.org/10.18632/oncotarget.24309 Text en Copyright: © 2018 Chakraborty et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review
Chakraborty, Chiranjib
Sharma, Ashish Ranjan
Sharma, Garima
Sarkar, Bimal Kumar
Lee, Sang-Soo
The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title_full The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title_fullStr The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title_full_unstemmed The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title_short The novel strategies for next-generation cancer treatment: miRNA combined with chemotherapeutic agents for the treatment of cancer
title_sort novel strategies for next-generation cancer treatment: mirna combined with chemotherapeutic agents for the treatment of cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839381/
https://www.ncbi.nlm.nih.gov/pubmed/29515800
http://dx.doi.org/10.18632/oncotarget.24309
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