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TMIGD1 acts as a tumor suppressor through regulation of p21Cip1/p27Kip1 in renal cancer
Renal cell carcinoma (RCC) is a high-risk metastasizing tumor with a poor prognosis and poorly understood mechanism. In this study, we demonstrate that transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelia...
Autores principales: | Meyer, Rosana D., Zou, Xueqing, Ali, Marwa, Ersoy, Esma, Bondzie, Philip Apraku, Lavaei, Mehrdad, Alexandrov, Ilya, Henderson, Joel, Rahimi, Nader |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839393/ https://www.ncbi.nlm.nih.gov/pubmed/29515762 http://dx.doi.org/10.18632/oncotarget.23822 |
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