CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer

Ovarian cancer (OC) has the highest rate of mortality among gynecological malignancy. Chemokine receptor CXCR2 in OC is associated with poor outcomes. However, the mechanisms by which CXCR2 regulates OC proliferation remain poorly understood. We generated CXCR2-positive cells from parental p53 wild-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ignacio, Rosa Mistica C., Dong, Yuan-Lin, Kabir, Syeda M., Choi, Hyeongjwa, Lee, Eun-Sook, Wilson, Andrew J., Beeghly-Fadiel, Alicia, Whalen, Margaret M., Son, Deok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839399/
https://www.ncbi.nlm.nih.gov/pubmed/29515768
http://dx.doi.org/10.18632/oncotarget.24231

Ejemplares similares

Ejemplares similares