Cargando…

Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Here we show that shotgun and targeted protein sequencing can be used to identify potential prognostic biomarkers in formalin-fixed paraffin-embedded specimens from 9 patients with PDAC with “short” survival (<12 months) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Dingyuan, Ansari, Daniel, Pawłowski, Krzysztof, Zhou, Qimin, Sasor, Agata, Welinder, Charlotte, Kristl, Theresa, Bauden, Monika, Rezeli, Melinda, Jiang, Yi, Marko-Varga, György, Andersson, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839402/ https://www.ncbi.nlm.nih.gov/pubmed/29515771 http://dx.doi.org/10.18632/oncotarget.23929

Ejemplares similares

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma
por: Bauden, Monika, et al.
Publicado: (2017)

Quantitative proteomics identifies brain acid soluble protein 1 (BASP1) as a prognostic biomarker candidate in pancreatic cancer tissue
por: Zhou, Qimin, et al.
Publicado: (2019)

Calcium-activated chloride channel regulator 1 as a prognostic biomarker in pancreatic ductal adenocarcinoma
por: Hu, Dingyuan, et al.
Publicado: (2018)

The role of quantitative mass spectrometry in the discovery of pancreatic cancer biomarkers for translational science
por: Ansari, Daniel, et al.
Publicado: (2014)

Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma
por: Hu, Dingyuan, et al.
Publicado: (2019)

YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling
por: Zhou, Qimin, et al.
Publicado: (2020)

Mass spectrometry-based analysis of formalin-fixed, paraffin-embedded distal cholangiocarcinoma identifies stromal thrombospondin-2 as a potential prognostic marker
por: Byrling, Johannes, et al.
Publicado: (2020)

Targeting dendritic cells in pancreatic ductal adenocarcinoma
por: Deicher, Anton, et al.
Publicado: (2018)

Proteomic and genomic profiling of pancreatic cancer
por: Ansari, Daniel, et al.
Publicado: (2019)

Proteomic analysis enables distinction of early‐ versus advanced‐stage lung adenocarcinomas
por: Kelemen, Olga, et al.
Publicado: (2020)

Moving towards high density clinical signature studies with a human proteome catalogue developing multiplexing mass spectrometry assay panels
por: Rezeli, Melinda, et al.
Publicado: (2011)

Proteomic profiling of extracellular vesicles reveals additional diagnostic biomarkers for myocardial infarction compared to plasma alone
por: Gidlöf, Olof, et al.
Publicado: (2019)

Analysis of Alpha-Synuclein in Malignant Melanoma – Development of a SRM Quantification Assay
por: Welinder, Charlotte, et al.
Publicado: (2014)

SPARC: A Potential Prognostic and Therapeutic Target in Pancreatic Cancer
por: Vaz, Juan, et al.
Publicado: (2015)

Correlation of histopathologic characteristics to protein expression and function in malignant melanoma
por: Welinder, Charlotte, et al.
Publicado: (2017)

Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data
por: Betancourt, Lazaro Hiram, et al.
Publicado: (2019)

A Protein Deep Sequencing Evaluation of Metastatic Melanoma Tissues
por: Welinder, Charlotte, et al.
Publicado: (2015)

Establishing a Southern Swedish Malignant Melanoma OMICS and biobank clinical capability
por: Welinder, Charlotte, et al.
Publicado: (2013)

The actual 5-year survivors of pancreatic ductal adenocarcinoma based on real-world data
por: Bengtsson, Axel, et al.
Publicado: (2020)

Clusterwise Peak Detection and Filtering Based on Spatial Distribution To Efficiently Mine Mass Spectrometry Imaging Data
por: Eriksson, Jonatan O., et al.
Publicado: (2019)

Outcome and evaluation of prognostic factors after pancreaticoduodenectomy for distal cholangiocarcinoma
por: Byrling, Johannes, et al.
Publicado: (2017)

Potential biomarkers for early detection of pancreatic ductal adenocarcinoma
por: Kriz, D., et al.
Publicado: (2020)

Non-invasive skin sampling of tryptophan/kynurenine ratio in vitro towards a skin cancer biomarker
por: Jankovskaja, Skaidre, et al.
Publicado: (2021)

Proteome alterations in pancreatic ductal adenocarcinoma
por: Pan, Sheng, et al.
Publicado: (2020)

Correction: Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue
por: Murillo, Jimmy Rodriguez, et al.
Publicado: (2018)

Automated phosphopeptide enrichment from minute quantities of frozen malignant melanoma tissue
por: Murillo, Jimmy Rodriguez, et al.
Publicado: (2018)

Topological Dissection of Proteomic Changes Linked to the Limbic Stage of Alzheimer’s Disease
por: Velásquez, Erika, et al.
Publicado: (2021)

Pancreatic cancer: disease dynamics, tumor biology and the role of the microenvironment
por: Ansari, Daniel, et al.
Publicado: (2018)

MSIWarp: A General Approach to Mass Alignment in Mass Spectrometry Imaging
por: Eriksson, Jonatan O., et al.
Publicado: (2020)

Thrombospondin-2 as a diagnostic biomarker for distal cholangiocarcinoma and pancreatic ductal adenocarcinoma
por: Byrling, J., et al.
Publicado: (2021)

Standardization developments for large scale biobanks in smoking related diseases - a model system for blood sample processing and storage
por: Malm, Johan, et al.
Publicado: (2013)

Case report of prostate ductal adenocarcinoma presenting with hematuria
por: Pawlowski, Jamie, et al.
Publicado: (2018)

Immune checkpoint therapy for pancreatic cancer
por: Johansson, Henrik, et al.
Publicado: (2016)

Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI
por: Kim, Yonghyo, et al.
Publicado: (2020)

Challenging the heterogeneity of disease presentation in malignant melanoma—impact on patient treatment
por: Marcell Szasz, A., et al.
Publicado: (2018)

Visualisation of H(2)O(2) penetration through skin indicates importance to develop pathway-specific epidermal sensing
por: Jankovskaja, Skaidre, et al.
Publicado: (2020)

Biobank resources for future patient care: developments, principles and concepts
por: Végvári, Ákos, et al.
Publicado: (2011)

Comparative Proteomic Profiling of Pancreatic Ductal Adenocarcinoma Cell Lines
por: Kim, Yikwon, et al.
Publicado: (2014)

Hyperdense Pancreatic Ductal Adenocarcinoma: Clinical Characteristics and Proteomic Landscape
por: Xu, He, et al.
Publicado: (2021)

Circulating nucleosomes as epigenetic biomarkers in pancreatic cancer
por: Bauden, Monika, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_av6f18g266q676oa64pqin3g8i