Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer

G protein-coupled receptors (GPCRs) are integral cell-surface proteins having a central role in tumor growth and metastasis. However, several GPCRs retain an atypical intracellular/nuclear location in various types of cancer. The pathological significance of this is currently unknown. Here we extend...

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Detalles Bibliográficos
Autores principales: Dubuc, Céléna, Savard, Martin, Bovenzi, Veronica, Lessard, Andrée, Fortier, Audrey, Côté, Jérôme, Neugebauer, Witold, Rizzolio, Flavio, Geha, Sameh, Giordano, Antonio, Chemtob, Sylvain, Gobeil, Fernand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839409/
https://www.ncbi.nlm.nih.gov/pubmed/29515778
http://dx.doi.org/10.18632/oncotarget.24009

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