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YJI-7 Suppresses ROS Production and Expression of Inflammatory Mediators via Modulation of p38MAPK and JNK Signaling in RAW 264.7 Macrophages
Chalcone, (2E)-1,3-Diphenylprop-2-en-1-one, and its synthetic derivatives are known to possess anti-oxidative and anti-inflammatory properties. In the present study, we prepared a novel synthetic chalcone compound, (E)-1-(4-hydroxyphenyl)-3-(2-(trifluoromethoxy)phenyl)prop-2-en-1-one name (YJI-7), a...
Autores principales: | Oh, Hye Jin, Magar, Til Bahadur Thapa, Pun, Nirmala Tilija, Lee, Yunji, Kim, Eun Hye, Lee, Eung-Seok, Park, Pil-Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839498/ https://www.ncbi.nlm.nih.gov/pubmed/28441795 http://dx.doi.org/10.4062/biomolther.2016.276 |
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