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Living Donor Re-transplantation for Repeated Acute Liver Failure

Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare. Herein, we describe a patient who underwent two emergency LTs for ALF, both from living donors. When she was 26 years old, she underwent...

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Autores principales: Ince, V., Kayaalp, C., Otan, E., Ozdemir, F., Dirican, A., Toprak, H. I., Aydin, C., Ara, C., Yilmaz, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Organ Transplantation Institute 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839631/
https://www.ncbi.nlm.nih.gov/pubmed/29531648
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author Ince, V.
Kayaalp, C.
Otan, E.
Ozdemir, F.
Dirican, A.
Toprak, H. I.
Aydin, C.
Ara, C.
Yilmaz, S.
author_facet Ince, V.
Kayaalp, C.
Otan, E.
Ozdemir, F.
Dirican, A.
Toprak, H. I.
Aydin, C.
Ara, C.
Yilmaz, S.
author_sort Ince, V.
collection PubMed
description Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare. Herein, we describe a patient who underwent two emergency LTs for ALF, both from living donors. When she was 26 years old, she underwent a right lobe living donor LT (LDLT) from her sister for ALF due to use of herbal weight loss medications. The next 3 years were uneventful but another ALF developed during a terminal stage pregnancy (37(th) week). Despite medical treatment, her liver functions worsened, and the baby was delivered by caesarean section. The second time, her brother was the donor and she recovered after the emergency right lobe re-LDLT. Both patient and baby were well at the 2-month follow-up. As far as we know, there is no reported similar case, and we concluded that LDLT is a paramount treatment option for both primary and secondary ALFs.
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spelling pubmed-58396312018-03-12 Living Donor Re-transplantation for Repeated Acute Liver Failure Ince, V. Kayaalp, C. Otan, E. Ozdemir, F. Dirican, A. Toprak, H. I. Aydin, C. Ara, C. Yilmaz, S. Int J Organ Transplant Med Case Report Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare. Herein, we describe a patient who underwent two emergency LTs for ALF, both from living donors. When she was 26 years old, she underwent a right lobe living donor LT (LDLT) from her sister for ALF due to use of herbal weight loss medications. The next 3 years were uneventful but another ALF developed during a terminal stage pregnancy (37(th) week). Despite medical treatment, her liver functions worsened, and the baby was delivered by caesarean section. The second time, her brother was the donor and she recovered after the emergency right lobe re-LDLT. Both patient and baby were well at the 2-month follow-up. As far as we know, there is no reported similar case, and we concluded that LDLT is a paramount treatment option for both primary and secondary ALFs. Avicenna Organ Transplantation Institute 2018 2018-02-01 /pmc/articles/PMC5839631/ /pubmed/29531648 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ince, V.
Kayaalp, C.
Otan, E.
Ozdemir, F.
Dirican, A.
Toprak, H. I.
Aydin, C.
Ara, C.
Yilmaz, S.
Living Donor Re-transplantation for Repeated Acute Liver Failure
title Living Donor Re-transplantation for Repeated Acute Liver Failure
title_full Living Donor Re-transplantation for Repeated Acute Liver Failure
title_fullStr Living Donor Re-transplantation for Repeated Acute Liver Failure
title_full_unstemmed Living Donor Re-transplantation for Repeated Acute Liver Failure
title_short Living Donor Re-transplantation for Repeated Acute Liver Failure
title_sort living donor re-transplantation for repeated acute liver failure
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839631/
https://www.ncbi.nlm.nih.gov/pubmed/29531648
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