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Sox7 promotes high-grade glioma by increasing VEGFR2-mediated vascular abnormality

High-grade glioma (HGG) is highly angiogenic, but antiangiogenic therapy has transient clinical benefit in only a fraction of patients. Vascular regulators of these heterogeneous responses remain undetermined. We found up-regulation of Sox7 and down-regulation of Sox17 in tumor endothelial cells (tE...

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Detalles Bibliográficos
Autores principales:	Kim, Il-Kug, Kim, Kangsan, Lee, Eunhyeong, Oh, Dong Sun, Park, Chan Soon, Park, Seongyeol, Yang, Jee Myung, Kim, Ju-Hee, Kim, Hyung-Seok, Shima, David T., Kim, Jeong Hoon, Hong, Seok Ho, Cho, Young Hyun, Kim, Young Hoon, Park, Jong Bae, Koh, Gou Young, Ju, Young Seok, Lee, Heung Kyu, Lee, Seungjoo, Kim, Injune
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839752/ https://www.ncbi.nlm.nih.gov/pubmed/29444818 http://dx.doi.org/10.1084/jem.20170123

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