Cargando…

Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity

Eliciting effective antitumor immune responses in patients who fail checkpoint inhibitor therapy is a critical challenge in cancer immunotherapy, and in such patients, tumor-associated myeloid cells and macrophages (TAMs) are promising therapeutic targets. We demonstrate in an autochthonous, poorly...

Descripción completa

Detalles Bibliográficos
Autores principales:	Perry, Curtis J., Muñoz-Rojas, Andrés R., Meeth, Katrina M., Kellman, Laura N., Amezquita, Robert A., Thakral, Durga, Du, Victor Y., Wang, Jake Xiao, Damsky, William, Kuhlmann, Alexandra L., Sher, Joel W., Bosenberg, Marcus, Miller-Jensen, Kathryn, Kaech, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839759/ https://www.ncbi.nlm.nih.gov/pubmed/29436395 http://dx.doi.org/10.1084/jem.20171435

Ejemplares similares

scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3′ mRNA profiling
por: Dura, Burak, et al.
Publicado: (2019)

Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity
por: Zhang, Xinyi, et al.
Publicado: (2022)

Remodeling the Tumor Myeloid Landscape to Enhance Antitumor Antibody Immunotherapies
por: Hussain, Khiyam, et al.
Publicado: (2021)

Synergy of cancer immunotherapy and radiotherapy
por: Mansfield, Aaron S., et al.
Publicado: (2015)

Mechanisms of synergy of radiotherapy and immunotherapy
por: Pilones, Karsten A, et al.
Publicado: (2015)

Decoding Melanoma Metastasis
por: Damsky, William E., et al.
Publicado: (2010)

Radiation and immunotherapy: emerging mechanisms of synergy
por: Breen, William G., et al.
Publicado: (2020)

B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors
por: Damsky, William, et al.
Publicado: (2019)

Cryoablation and immunotherapy: an overview of evidence on its synergy
por: Aarts, B. M., et al.
Publicado: (2019)

Cryoablation and Immunotherapy: An Enthralling Synergy to Confront the Tumors
por: Yakkala, Chakradhar, et al.
Publicado: (2019)

Cryoablation and Immunotherapy: An Enthralling Synergy for Cancer Treatment
por: Medlej, Zain al Abidine, et al.
Publicado: (2023)

The next age of immunotherapy: optimisation, stratification and therapeutic synergies
por: Halama, Niels
Publicado: (2018)

Clinical evidence for synergy between immunotherapy and radiotherapy (SITAR)
por: Gill, Suki, et al.
Publicado: (2022)

A Biosurfactant-Sophorolipid Acts in Synergy with Antibiotics to Enhance Their Efficiency
por: Joshi-Navare, Kasturi, et al.
Publicado: (2013)

Muscarinic acetylcholine receptors act in synergy to facilitate learning and memory
por: Leaderbrand, Katherine, et al.
Publicado: (2016)

Discovery of a Structurally Unique Small Molecule that Inhibits Protein Synthesis
por: Thakral, Durga, et al.
Publicado: (2017)

Advances of Electroporation-Related Therapies and the Synergy with Immunotherapy in Cancer Treatment
por: Gong, Xuan, et al.
Publicado: (2022)

Optimizing the synergy between stereotactic radiosurgery and immunotherapy for brain metastases
por: Yoo, Kelly H., et al.
Publicado: (2023)

IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy
por: Zhou, Ting, et al.
Publicado: (2020)

Hyperglycemia acts in synergy with hypoxia to maintain the pro-inflammatory phenotype of macrophages
por: Morey, Mangesh, et al.
Publicado: (2019)

Luteolin Suppresses the Proliferation of Gastric Cancer Cells and Acts in Synergy with Oxaliplatin
por: Ren, Li-Qun, et al.
Publicado: (2020)

Novel Cancer Immunotherapies and Antitumor Immunity
por: Zhao, Lei, et al.
Publicado: (2019)

Synergy between Proteasome Inhibitors and Imatinib Mesylate in Chronic Myeloid Leukemia
por: Hu, Zheng, et al.
Publicado: (2009)

TLR4 and NKT Cell Synergy in Immunotherapy against Visceral Leishmaniasis
por: Karmakar, Subir, et al.
Publicado: (2012)

Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6
por: Andersson, Karin M.E., et al.
Publicado: (2015)

Self-extracellular RNA acts in synergy with exogenous danger signals to promote inflammation
por: Noll, Frederik, et al.
Publicado: (2017)

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
por: Braun, Theodore P., et al.
Publicado: (2019)

Antitumoral effect of Ocoxin on acute myeloid leukemia
por: Díaz-Rodríguez, Elena, et al.
Publicado: (2016)

Harnessing the antitumor potential of macrophages for cancer immunotherapy
por: Long, Kristen B, et al.
Publicado: (2013)

Creatine in T Cell Antitumor Immunity and Cancer Immunotherapy
por: Li, Bo, et al.
Publicado: (2021)

IL-1 receptor–associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy
por: Tunalı, Gürcan, et al.
Publicado: (2023)

Mechanistic Insights into Synergy between Melanin-Targeting Radioimmunotherapy and Immunotherapy in Experimental Melanoma
por: Malo, Mackenzie E., et al.
Publicado: (2020)

Synergy of Polydopamine Nanovaccine and Endostar Alginate Hydrogel for Improving Antitumor Immune Responses Against Colon Tumor
por: Yang, Ying, et al.
Publicado: (2022)

The landscape of novel and complementary targets for immunotherapy: an analysis of gene expression in the tumor microenvironment
por: Gaffney, Stephen G., et al.
Publicado: (2019)

Perils of inappropriate antibiotic exposure in cancer patients. A call to fast-acting synergy
por: Pagani, L
Publicado: (2011)

The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling
por: Storer Samaniego, Cheryl, et al.
Publicado: (2015)

Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells
por: Warth, Benedikt, et al.
Publicado: (2019)

Short-term neuronal and synaptic plasticity act in synergy for deviance detection in spiking networks
por: Kern, Felix Benjamin, et al.
Publicado: (2023)

DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune cell activation
por: Xiao, Qian, et al.
Publicado: (2018)

Antitumor effects of targeting myeloid-derived suppressive cells
por: Zeng, Dong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_83t34tskdais9cu2ba4siqhgm3