Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

Host-protective caspase-1 activity must be tightly regulated to prevent pathology, but mechanisms controlling the duration of cellular caspase-1 activity are unknown. Caspase-1 is activated on inflammasomes, signaling platforms that facilitate caspase-1 dimerization and autoprocessing. Previous stud...

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Detalles Bibliográficos
Autores principales: Boucher, Dave, Monteleone, Mercedes, Coll, Rebecca C., Chen, Kaiwen W., Ross, Connie M., Teo, Jessica L., Gomez, Guillermo A., Holley, Caroline L., Bierschenk, Damien, Stacey, Katryn J., Yap, Alpha S., Bezbradica, Jelena S., Schroder, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839769/
https://www.ncbi.nlm.nih.gov/pubmed/29432122
http://dx.doi.org/10.1084/jem.20172222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839769/
https://www.ncbi.nlm.nih.gov/pubmed/29432122
http://dx.doi.org/10.1084/jem.20172222

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