Cargando…
Metaplastic Cdx2-depleted cells can be very disruptive neighbors
In this issue of JEM, Balbinot et al. (https://doi.org/10.1084/jem.20170934) describe an original mechanism where Cdx2 inactivation regulates intestinal metaplastic to neoplastic transition in a paracrine fashion. Surprisingly, the target cells are neighboring “normal” Cdx2-positive cells.
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839770/ https://www.ncbi.nlm.nih.gov/pubmed/29440363 http://dx.doi.org/10.1084/jem.20180215 |