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The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression
The role of formins in microtubules is not well understood. In this study, we have investigated the mechanism by which INF2, a formin mutated in degenerative renal and neurological hereditary disorders, controls microtubule acetylation. We found that silencing of INF2 in epithelial RPE-1 cells produ...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839776/ https://www.ncbi.nlm.nih.gov/pubmed/29321169 http://dx.doi.org/10.1083/jcb.201702157 |