Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling

Exosomes are small endosome-derived extracellular vesicles implicated in cell–cell communication and are secreted by living cells when multivesicular bodies (MVBs) fuse with the plasma membrane (PM). Current techniques to study exosome physiology are based on isolation procedures after secretion, pr...

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Detalles Bibliográficos
Autores principales: Verweij, Frederik Johannes, Bebelman, Maarten P., Jimenez, Connie R., Garcia-Vallejo, Juan J., Janssen, Hans, Neefjes, Jacques, Knol, Jaco C., de Goeij-de Haas, Richard, Piersma, Sander R., Baglio, S. Rubina, Verhage, Matthijs, Middeldorp, Jaap M., Zomer, Anoek, van Rheenen, Jacco, Coppolino, Marc G., Hurbain, Ilse, Raposo, Graça, Smit, Martine J., Toonen, Ruud F.G., van Niel, Guillaume, Pegtel, D. Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839777/
https://www.ncbi.nlm.nih.gov/pubmed/29339438
http://dx.doi.org/10.1083/jcb.201703206

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