SNAREing an ARP requires a LIR

The fusion of autophagosomes with lysosomes is an obligatory step in the self-eating process of autophagy. In this issue, Kumar et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201708039) identify a protein complex, the autophagosome recognition particle (ARP), that chaperones a key SNARE, sy...

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Detalles Bibliográficos
Autor principal: Tooze, Sharon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839799/
https://www.ncbi.nlm.nih.gov/pubmed/29449316
http://dx.doi.org/10.1083/jcb.201801104
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author Tooze, Sharon A.
author_facet Tooze, Sharon A.
author_sort Tooze, Sharon A.
collection PubMed
description The fusion of autophagosomes with lysosomes is an obligatory step in the self-eating process of autophagy. In this issue, Kumar et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201708039) identify a protein complex, the autophagosome recognition particle (ARP), that chaperones a key SNARE, syntaxin 17, to the autophagosome membrane. Intriguingly, this protein complex coordinates both delivery and membrane insertion as a prelude to fusion.
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spelling pubmed-58397992018-09-05 SNAREing an ARP requires a LIR Tooze, Sharon A. J Cell Biol Commentaries The fusion of autophagosomes with lysosomes is an obligatory step in the self-eating process of autophagy. In this issue, Kumar et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201708039) identify a protein complex, the autophagosome recognition particle (ARP), that chaperones a key SNARE, syntaxin 17, to the autophagosome membrane. Intriguingly, this protein complex coordinates both delivery and membrane insertion as a prelude to fusion. Rockefeller University Press 2018-03-05 /pmc/articles/PMC5839799/ /pubmed/29449316 http://dx.doi.org/10.1083/jcb.201801104 Text en © 2018 Tooze http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Commentaries
Tooze, Sharon A.
SNAREing an ARP requires a LIR
title SNAREing an ARP requires a LIR
title_full SNAREing an ARP requires a LIR
title_fullStr SNAREing an ARP requires a LIR
title_full_unstemmed SNAREing an ARP requires a LIR
title_short SNAREing an ARP requires a LIR
title_sort snareing an arp requires a lir
topic Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839799/
https://www.ncbi.nlm.nih.gov/pubmed/29449316
http://dx.doi.org/10.1083/jcb.201801104
work_keys_str_mv AT toozesharona snareinganarprequiresalir

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