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Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α
BACKGROUND: Curcumin has been used as an alternative medicine for the treatment of infantile hemangiomas (IHs); however, the mechanism underlying the effectiveness of curcumin in IHs remains largely unclear. METHODS: In this study, we isolated primary human hemangioma endothelial cells (HemECs) from...
Autores principales: | Lou, Suhui, Wang, Yanfang, Yu, Zujiang, Guan, Kelei, Kan, Quancheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839849/ https://www.ncbi.nlm.nih.gov/pubmed/29443732 http://dx.doi.org/10.1097/MD.0000000000009562 |
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