Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

Adipocytes possess remarkable adaptive capacity to respond to nutrient excess, fasting or cold exposure, and thus are an important cell type to maintain proper metabolic health. While the endoplasmic reticulum (ER) is a critical organelle for cellular homeostasis, the mechanisms that mediate adaptat...

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Detalles Bibliográficos
Autores principales: Bartelt, Alexander, Widenmaier, Scott B., Schlein, Christian, Johann, Kornelia, Goncalves, Renata L. S., Eguchi, Kosei, Fischer, Alexander W., Parlakgül, Günes, Snyder, Nicole A., Nguyen, Truc B., Bruns, Oliver T., Franke, Daniel, Bawendi, Moungi G., Lynes, Matthew D., Leiria, Luiz O., Tseng, Yu-Hua, Inouye, Karen E., Arruda, Ana Paula, Hotamisligil, Gökhan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839993/
https://www.ncbi.nlm.nih.gov/pubmed/29400713
http://dx.doi.org/10.1038/nm.4481

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