Congenital Zika Virus Infection as a Silent Pathology With Loss of Neurogenic Output in the Fetal Brain

Zika virus (ZIKV) is a flavivirus with teratogenic effects on the fetal brain, but the spectrum of brain injury is unknown, particularly when ultrasound imaging is normal. In a pregnant pigtail macaque (Macaca nemestrina) model, we demonstrate that ZIKV injury to the fetal brain was significant even...

Descripción completa

Detalles Bibliográficos
Autores principales: Adams Waldorf, Kristina M., Nelson, Branden R., Stencel-Baerenwald, Jennifer E., Studholme, Colin, Kapur, Raj P., Armistead, Blair, Walker, Christie L., Merillat, Sean, Vornhagen, Jay, Tisoncik-Go, Jennifer, Baldessari, Audrey, Coleman, Michelle, Dighe, Manjiri K., Shaw, Dennis W.W., Roby, Justin A., Santana-Ufret, Veronica, Boldenow, Erica, Li, Junwei, Gao, Xiaohu, Davis, Michael A., Swanstrom, Jesica A., Jensen, Kara, Widman, Douglas G., Baric, Ralph S., Medwid, Joseph T., Hanley, Kathryn A., Ogle, Jason, Gough, G. Michael, Lee, Wonsok, English, Chris, Durning, W. McIntyre, Thiel, Jeff, Gatenby, Chris, Dewey, Elyse C., Fairgrieve, Marian R., Hodge, Rebecca D., Grant, Richard F., Kuller, LaRene, Dobyns, William B., Hevner, Robert F., Gale, Michael, Rajagopal, Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839998/
https://www.ncbi.nlm.nih.gov/pubmed/29400709
http://dx.doi.org/10.1038/nm.4485

Ejemplares similares

Ejemplares similares