The antidepressant action of 3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid is mediated by phosphorylation of histone deacetylase 5

3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid (CPP), a competitive N-methyl-D-aspartate (NMDA) receptor antagonist, produces rapid antidepressant-like effects in animal models of depression. However, the molecular mechanisms underlying these behavioral actions remain unknown. Here, we demonstr...

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Detalles Bibliográficos
Autores principales: Park, Min Hyeop, Choi, Miyeon, Kim, Yong-Seok, Son, Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840074/
https://www.ncbi.nlm.nih.gov/pubmed/29520168
http://dx.doi.org/10.4196/kjpp.2018.22.2.155

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