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The Phosphorylation of CCR6 on Distinct Ser/Thr Residues in the Carboxyl Terminus Differentially Regulates Biological Function

CCR6 is a G protein-coupled receptor (GPCR) that recognizes a single chemokine ligand, CCL20 and is primarily expressed by leukocytes. Upon ligand binding, CCR6 activates Gαi heterotrimeric G proteins to induce various potential cellular outcomes through context-specific cell signaling. It is well k...

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Detalles Bibliográficos
Autores principales:	Lu, Mei-Yi, Lu, Syuan-Shao, Chang, Shiann-Luen, Liao, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840145/ https://www.ncbi.nlm.nih.gov/pubmed/29552015 http://dx.doi.org/10.3389/fimmu.2018.00415

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