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Independent Evolution of Strychnine Recognition by Bitter Taste Receptor Subtypes

The 25 human bitter taste receptors (hT2Rs) recognize thousands of structurally and chemically diverse bitter substances. The binding modes of human bitter taste receptors hT2R10 and hT2R46, which are responsible for strychnine recognition, were previously established using site-directed mutagenesis...

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Detalles Bibliográficos
Autores principales:	Xue, Ava Yuan, Di Pizio, Antonella, Levit, Anat, Yarnitzky, Tali, Penn, Osnat, Pupko, Tal, Niv, Masha Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840161/ https://www.ncbi.nlm.nih.gov/pubmed/29552563 http://dx.doi.org/10.3389/fmolb.2018.00009

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