Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis

T cells reacting to self-components can promote tissue damage when escaping tolerogenic control mechanisms which may result in autoimmune disease. The current treatments for these disorders are not antigen (Ag) specific and can compromise host immunity through chronic suppression. We have previously...

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Detalles Bibliográficos
Autores principales: LaMothe, Robert A., Kolte, Pallavi N., Vo, Trinh, Ferrari, Joseph D., Gelsinger, Tracy C., Wong, Jodie, Chan, Victor T., Ahmed, Sinthia, Srinivasan, Aditi, Deitemeyer, Patrick, Maldonado, Roberto A., Kishimoto, Takashi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840162/
https://www.ncbi.nlm.nih.gov/pubmed/29552007
http://dx.doi.org/10.3389/fimmu.2018.00281

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