Cargando…

Variants of the EAAT2 Glutamate Transporter Gene Promoter Are Associated with Cerebral Palsy in Preterm Infants

Preterm delivery is associated with neurodevelopmental impairment caused by environmental and genetic factors. Dysfunction of the excitatory amino acid transporter 2 (EAAT2) and the resultant impaired glutamate uptake can lead to neurological disorders. In this study, we investigated the role of sin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajatileka, Shavanthi, Odd, David, Robinson, Matthew T., Spittle, Alexandra C., Dwomoh, Louis, Williams, Maggie, Harding, David, Wagstaff, Miles, Owen, Marie, Crosby, Charlene, Ching, Jared, Molnár, Elek, Luyt, Karen, Váradi, Anikó
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840247/ https://www.ncbi.nlm.nih.gov/pubmed/28271401 http://dx.doi.org/10.1007/s12035-017-0462-1

Ejemplares similares

Detection of three closely located single nucleotide polymorphisms in the EAAT2 promoter: comparison of single-strand conformational polymorphism (SSCP), pyrosequencing and Sanger sequencing
por: Rajatileka, Shavanthi, et al.
Publicado: (2014)

Isolation of human genomic DNA for genetic analysis from premature neonates: a comparison between newborn dried blood spots, whole blood and umbilical cord tissue
por: Rajatileka, Shavanthi, et al.
Publicado: (2013)

MyRIP interaction with MyoVa on secretory granules is controlled by the cAMP-PKA pathway
por: Brozzi, Flora, et al.
Publicado: (2012)

Glutamate Transporters EAAT4 and EAAT5 Are Expressed in Vestibular Hair Cells and Calyx Endings
por: Dalet, Antoine, et al.
Publicado: (2012)

Glutamate transporters, EAAT1 and EAAT2, are potentially important in the pathophysiology and treatment of schizophrenia and affective disorders
por: Parkin, Georgia M, et al.
Publicado: (2018)

Glutamate Transporters EAAT2 and EAAT5 Differentially Shape Synaptic Transmission from Rod Bipolar Cell Terminals
por: Tang, Fu-Sheng, et al.
Publicado: (2022)

Molecular Dynamics Simulations of the Mammalian Glutamate Transporter EAAT3
por: Heinzelmann, Germano, et al.
Publicado: (2014)

Excitatory Amino Acid Transporters (EAATs): Glutamate Transport and Beyond
por: Magi, Simona, et al.
Publicado: (2019)

The Neuronal Glutamate Transporter EAAT3 in Obsessive-Compulsive Disorder
por: Escobar, Angélica P., et al.
Publicado: (2019)

Effects of tranexamic acid on the activity of glutamate transporter EAAT3
por: Shin, Hyun-Jung, et al.
Publicado: (2020)

EAAT5 Glutamate Transporter-Mediated Inhibition in the Vertebrate Retina
por: Lukasiewcz, Peter D., et al.
Publicado: (2021)

The Glutamate Transporter Subtypes EAAT4 and EAATs 1-3 Transport Glutamate with Dramatically Different Kinetics and Voltage Dependence but Share a Common Uptake Mechanism
por: Mim, Carsten, et al.
Publicado: (2005)

LRET-based distance measurements in the mammalian glutamate transporter EAAT3
por: Saha, Kusumika, et al.
Publicado: (2012)

Impaired K(+) binding to glial glutamate transporter EAAT1 in migraine
por: Kovermann, Peter, et al.
Publicado: (2017)

Blood glutamate EAAT(2)-cell grabbing therapy in cerebral ischemia
por: Pérez-Mato, María, et al.
Publicado: (2018)

Shaping of Signal Transmission at the Photoreceptor Synapse by EAAT2 Glutamate Transporters
por: Niklaus, Stephanie, et al.
Publicado: (2017)

Neurochemical and behavioral characterization of neuronal glutamate transporter EAAT3 heterozygous mice
por: González, Luis F., et al.
Publicado: (2017)

Effects of clonidine on the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes
por: Woo, Jae Hee, et al.
Publicado: (2012)

Polymorphism of the Glutamate Transporter Protein EAAT2 and Migraine Transformation into Chronic Daily Headache
por: Shin, Hae-Eun, et al.
Publicado: (2011)

Remote Ischaemic Preconditioning Accelerates Brain to Blood Glutamate Efflux via EAATs-mediated Transport
por: Končekova, Jana, et al.
Publicado: (2023)

Klotho Sensitivity of the Neuronal Excitatory Amino Acid Transporters EAAT3 and EAAT4
por: Almilaji, Ahmad, et al.
Publicado: (2013)

Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x(c)(−)
por: Bridges, Richard J., et al.
Publicado: (2008)

A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke
por: Mallolas, Judith, et al.
Publicado: (2006)

Position of the Third Na(+) Site in the Aspartate Transporter Glt(Ph) and the Human Glutamate Transporter, EAAT1
por: Bastug, Turgut, et al.
Publicado: (2012)

Doxepin and imipramine but not fluoxetine reduce the activity of the rat glutamate transporter EAAT3 expressed in Xenopus oocytes
por: Park, Hye Jin, et al.
Publicado: (2015)

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease
por: Takahashi, Kou, et al.
Publicado: (2015)

Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells
por: Perkins, Emma M, et al.
Publicado: (2018)

Prophylactic Activation of Shh Signaling Attenuates TBI-Induced Seizures in Zebrafish by Modulating Glutamate Excitotoxicity through Eaat2a
por: Hentig, James, et al.
Publicado: (2021)

Aquaporin-4–binding autoantibodies in patients with neuromyelitis optica impair glutamate transport by down-regulating EAAT2
por: Hinson, Shannon R., et al.
Publicado: (2008)

The Accessibility in the External Part of the TM5 of the Glutamate Transporter EAAT1 Is Conformationally Sensitive during the Transport Cycle
por: Zhang, Xiuping, et al.
Publicado: (2012)

Developmental and Activity Dependent Regulation of Ionotropic Glutamate Receptors at Synapses
por: Molnar, Elek, et al.
Publicado: (2002)

The closer the better: does better access to outpatient care prevent hospitalization?
por: Elek, Péter, et al.
Publicado: (2019)

Treatment for Post-hemorrhagic Ventricular Dilatation: A Multiple-Treatment Meta-Analysis
por: Mahoney, Liam, et al.
Publicado: (2020)

Loss of glutamate transporter eaat2a leads to aberrant neuronal excitability, recurrent epileptic seizures, and basal hypoactivity
por: Hotz, Adriana L., et al.
Publicado: (2021)

PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer’s disease
por: Perrin, Florian, et al.
Publicado: (2023)

Glutamate Transport and Preterm Brain Injury
por: Pregnolato, Silvia, et al.
Publicado: (2019)

Gateways for Glutamate Neuroprotection in Parkinson’s Disease (PD): Essential Role of EAAT3 and NCX1 Revealed in an In Vitro Model of PD
por: Piccirillo, Silvia, et al.
Publicado: (2020)

Estrogen and progesterone attenuate glutamate neurotoxicity via regulation of EAAT3 and GLT-1 in a rat model of ischemic stroke
por: Nematipour, Sara, et al.
Publicado: (2020)

Astrocytic transcription factor REST upregulates glutamate transporter EAAT2, protecting dopaminergic neurons from manganese-induced excitotoxicity
por: Pajarillo, Edward, et al.
Publicado: (2021)

Cellular Physiology and Pathophysiology of EAAT Anion Channels
por: Kovermann, Peter, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uf0qt37cj63fkqf5mpb3o52nmt