Direct Detection of Unamplified Pathogen RNA in Blood Lysate using an Integrated Lab-in-a-Stick Device and Ultrabright SERS Nanorattles

Direct detection of genetic biomarkers in body fluid lysate without target amplification will revolutionize nucleic acid-based diagnostics. However, the low concentration of target sequences makes this goal challenging. We report a method for direct detection of pathogen RNA in blood lysate using a...

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Detalles Bibliográficos
Autores principales: Ngo, Hoan T., Freedman, Elizabeth, Odion, Ren Abelard, Strobbia, Pietro, De Silva Indrasekara, Agampodi Swarnapali, Vohra, Priya, Taylor, Steve M., Vo-Dinh, Tuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840326/
https://www.ncbi.nlm.nih.gov/pubmed/29511216
http://dx.doi.org/10.1038/s41598-018-21615-3

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