Rb is required for retinal angiogenesis and lamination

Retinoblastoma tumor suppressor (Rb) promotes cell cycle exit, survival, differentiation, and tumor suppression in the retina. Here, we show it is also essential for vascularization and lamination. Despite minimal effects on Hif1a target expression, intraretinal vascular plexi did not form in the Rb...

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Detalles Bibliográficos
Autores principales: Zhou, Yi, Wei, Ran, Zhang, Liu, Chen, Yongjiang, Lu, Suying, Liang, Chen, Wang, Yujiao, Xiao, Lirong, Zhang, Junjun, Bremner, Rod, Chen, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840357/
https://www.ncbi.nlm.nih.gov/pubmed/29511172
http://dx.doi.org/10.1038/s41419-018-0411-6

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