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Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?
Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440 000 cases were reported. Large-scale screening of populations at risk, drug donations, and efforts by national and international stakeholders have brought the epidemic under control with <22...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840517/ https://www.ncbi.nlm.nih.gov/pubmed/29396200 http://dx.doi.org/10.1016/j.pt.2017.11.008 |
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| author | Büscher, Philippe Bart, Jean-Mathieu Boelaert, Marleen Bucheton, Bruno Cecchi, Giuliano Chitnis, Nakul Courtin, David Figueiredo, Luisa M. Franco, José-Ramon Grébaut, Pascal Hasker, Epco Ilboudo, Hamidou Jamonneau, Vincent Koffi, Mathurin Lejon, Veerle MacLeod, Annette Masumu, Justin Matovu, Enock Mattioli, Raffaele Noyes, Harry Picado, Albert Rock, Kat S. Rotureau, Brice Simo, Gustave Thévenon, Sophie Trindade, Sandra Truc, Philippe Van Reet, Nick |
| author_facet | Büscher, Philippe Bart, Jean-Mathieu Boelaert, Marleen Bucheton, Bruno Cecchi, Giuliano Chitnis, Nakul Courtin, David Figueiredo, Luisa M. Franco, José-Ramon Grébaut, Pascal Hasker, Epco Ilboudo, Hamidou Jamonneau, Vincent Koffi, Mathurin Lejon, Veerle MacLeod, Annette Masumu, Justin Matovu, Enock Mattioli, Raffaele Noyes, Harry Picado, Albert Rock, Kat S. Rotureau, Brice Simo, Gustave Thévenon, Sophie Trindade, Sandra Truc, Philippe Van Reet, Nick |
| collection | PubMed |
| description | Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440 000 cases were reported. Large-scale screening of populations at risk, drug donations, and efforts by national and international stakeholders have brought the epidemic under control with <2200 cases in 2016. The World Health Organization (WHO) has set the goals of gambiense-HAT elimination as a public health problem for 2020, and of interruption of transmission to humans for 2030. Latent human infections and possible animal reservoirs may challenge these goals. It remains largely unknown whether, and to what extend, they have an impact on gambiense-HAT transmission. We argue that a better understanding of the contribution of human and putative animal reservoirs to gambiense-HAT epidemiology is mandatory to inform elimination strategies. |
| format | Online Article Text |
| id | pubmed-5840517 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Elsevier Science |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-58405172018-03-08 Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? Büscher, Philippe Bart, Jean-Mathieu Boelaert, Marleen Bucheton, Bruno Cecchi, Giuliano Chitnis, Nakul Courtin, David Figueiredo, Luisa M. Franco, José-Ramon Grébaut, Pascal Hasker, Epco Ilboudo, Hamidou Jamonneau, Vincent Koffi, Mathurin Lejon, Veerle MacLeod, Annette Masumu, Justin Matovu, Enock Mattioli, Raffaele Noyes, Harry Picado, Albert Rock, Kat S. Rotureau, Brice Simo, Gustave Thévenon, Sophie Trindade, Sandra Truc, Philippe Van Reet, Nick Trends Parasitol Article Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440 000 cases were reported. Large-scale screening of populations at risk, drug donations, and efforts by national and international stakeholders have brought the epidemic under control with <2200 cases in 2016. The World Health Organization (WHO) has set the goals of gambiense-HAT elimination as a public health problem for 2020, and of interruption of transmission to humans for 2030. Latent human infections and possible animal reservoirs may challenge these goals. It remains largely unknown whether, and to what extend, they have an impact on gambiense-HAT transmission. We argue that a better understanding of the contribution of human and putative animal reservoirs to gambiense-HAT epidemiology is mandatory to inform elimination strategies. Elsevier Science 2018-03 /pmc/articles/PMC5840517/ /pubmed/29396200 http://dx.doi.org/10.1016/j.pt.2017.11.008 Text en © 2017 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Article Büscher, Philippe Bart, Jean-Mathieu Boelaert, Marleen Bucheton, Bruno Cecchi, Giuliano Chitnis, Nakul Courtin, David Figueiredo, Luisa M. Franco, José-Ramon Grébaut, Pascal Hasker, Epco Ilboudo, Hamidou Jamonneau, Vincent Koffi, Mathurin Lejon, Veerle MacLeod, Annette Masumu, Justin Matovu, Enock Mattioli, Raffaele Noyes, Harry Picado, Albert Rock, Kat S. Rotureau, Brice Simo, Gustave Thévenon, Sophie Trindade, Sandra Truc, Philippe Van Reet, Nick Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title | Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title_full | Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title_fullStr | Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title_full_unstemmed | Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title_short | Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination? |
| title_sort | do cryptic reservoirs threaten gambiense-sleeping sickness elimination? |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840517/ https://www.ncbi.nlm.nih.gov/pubmed/29396200 http://dx.doi.org/10.1016/j.pt.2017.11.008 |
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