Middle East respiratory syndrome: what we learned from the 2015 outbreak in the Republic of Korea

Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS case...

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Detalles Bibliográficos
Autores principales: Oh, Myoung-don, Park, Wan Beom, Park, Sang-Won, Choe, Pyoeng Gyun, Bang, Ji Hwan, Song, Kyoung-Ho, Kim, Eu Suk, Kim, Hong Bin, Kim, Nam Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840604/
https://www.ncbi.nlm.nih.gov/pubmed/29506344
http://dx.doi.org/10.3904/kjim.2018.031
Descripción
Sumario:Middle East Respiratory Syndrome coronavirus (MERS-CoV) was first isolated from a patient with severe pneumonia in 2012. The 2015 Korea outbreak of MERSCoV involved 186 cases, including 38 fatalities. A total of 83% of transmission events were due to five superspreaders, and 44% of the 186 MERS cases were the patients who had been exposed in nosocomial transmission at 16 hospitals. The epidemic lasted for 2 months and the government quarantined 16,993 individuals for 14 days to control the outbreak. This outbreak provides a unique opportunity to fill the gap in our knowledge of MERS-CoV infection. Therefore, in this paper, we review the literature on epidemiology, virology, clinical features, and prevention of MERS-CoV, which were acquired from the 2015 Korea outbreak of MERSCoV.

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