Cargando…

Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway

The present study investigated the inhibitory effects of apatinib on the proliferation of the SMMC-7721 hepatocellular carcinoma cell line to explore the possible mechanism. The MTT assay was used to detect the inhibitory effects of the different concentrations of apatinib on the proliferation of SM...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hua, Cao, Yumei, Chen, Yuru, Li, Guangxi, Yu, Hanshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840725/ https://www.ncbi.nlm.nih.gov/pubmed/29552208 http://dx.doi.org/10.3892/ol.2018.8031

Ejemplares similares

Mytoxin B and Myrothecine A Induce Apoptosis in Human Hepatocarcinoma Cell Line SMMC-7721 via PI3K/Akt Signaling Pathway
por: Song, Huiliang, et al.
Publicado: (2019)

Effect of Oleanolic Acid on Apoptosis and Autophagy of SMMC-7721 Hepatoma Cells
por: Zhou, Weipeng, et al.
Publicado: (2020)

Effects of miRNA-140 on the Growth and Clinical Prognosis of SMMC-7721 Hepatocellular Carcinoma Cell Line
por: Kong, Cun-qing, et al.
Publicado: (2021)

Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma cell line SMMC-7721
por: Liu, Run-Tian, et al.
Publicado: (2017)

Mechanism of Arctigenin-Induced Specific Cytotoxicity against Human Hepatocellular Carcinoma Cell Lines: Hep G2 and SMMC7721
por: Lu, Zheng, et al.
Publicado: (2015)

Gallic acid as a selective anticancer agent that induces apoptosis in SMMC-7721 human hepatocellular carcinoma cells
por: SUN, GUOJUN, et al.
Publicado: (2016)

Induction of apoptosis by an oleanolic acid derivative in SMMC-7721 human hepatocellular carcinoma cells is associated with mitochondrial dysfunction
por: Fan, Xinfeng, et al.
Publicado: (2018)

PE-induced apoptosis in SMMC-7721 cells: Involvement of Erk and Stat signalling pathways
por: XUE, LI, et al.
Publicado: (2014)

Retraction: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma cell line SMMC-7721
Publicado: (2021)

Composition of Lycium barbarum polysaccharides and their apoptosis-inducing effect on human hepatoma SMMC-7721 cells
por: Zhang, Qian, et al.
Publicado: (2015)

Apoptosis in Human Hepatoma Cell Line SMMC‐7721 Induced by Water‐soluble Macromolecular Components of Artemisia capillaris Thunberg
por: Hu, Yi Qiao, et al.
Publicado: (2000)

Effects of SSd Combined with Radiation on Inhibiting SMMC-7721 Hepatoma Cell Growth
por: Wang, Bao-feng, et al.
Publicado: (2014)

Expression of concern: Effects of LncRNA-HOST2 on cell proliferation, migration, invasion and apoptosis of human hepatocellular carcinoma cell line SMMC-7721
Publicado: (2020)

Ivalin Induces Mitochondria-Mediated Apoptosis Associated with the NF-κB Activation in Human Hepatocellular Carcinoma SMMC-7721 Cells
por: Han, Zhuo, et al.
Publicado: (2019)

Knockdown of the Sonic Hedgehog (SHH) Gene Inhibits Proliferation of Hep3B and SMMC-7721 Hepatocellular Carcinoma Cells via the PI3K/Akt/PCK1 Signaling Pathway
por: Chen, Youping, et al.
Publicado: (2019)

Evodiamine Induces Apoptosis in SMMC-7721 and HepG2 Cells by Suppressing NOD1 Signal Pathway
por: Guo, Xing-Xian, et al.
Publicado: (2018)

Casticin inhibits epithelial-mesenchymal transition of liver cancer stem cells of the SMMC-7721 cell line through downregulating Twist
por: HE, MENG, et al.
Publicado: (2014)

Plumbagin promotes human hepatoma SMMC-7721 cell apoptosis via caspase-3/vimentin signal-mediated EMT
por: Wei, Yanfei, et al.
Publicado: (2019)

Cytotoxic Activities, SAR and Anti-Invasion Effects of Butylphthalide Derivatives on Human Hepatocellular Carcinoma SMMC7721 Cells
por: Hu, Yihan, et al.
Publicado: (2015)

Anti-Invasion and Antimetastatic Effects of Porcine Recombinant NK-lysin on SMMC-7721 Human Hepatocellular Carcinoma Cells
por: Fan, Kuohai, et al.
Publicado: (2019)

Effects of magnetic nanoparticles of Fe(3)O(4) combinated with gambogic acid on apoptosis of SMMC-7721 cells
por: Tian, Liang, et al.
Publicado: (2015)

Effects of Sinapic Acid Combined with Cisplatin on the Apoptosis and Autophagy of the Hepatoma Cells HepG2 and SMMC-7721
por: Zhao, Jian, et al.
Publicado: (2021)

Synergistic Effect of Functionalized Nickel Nanoparticles and Quercetin on Inhibition of the SMMC-7721 Cells Proliferation
por: Guo, Dadong, et al.
Publicado: (2009)

Autophagy induced by baicalin involves downregulation of CD147 in SMMC-7721 cells in vitro
por: ZHANG, XIANJIAO, et al.
Publicado: (2011)

Anti-Migration Effects of Gekko Sulfated Glycopeptide on Human Hepatoma SMMC-7721 Cells
por: Wu, Xiong-Zhi, et al.
Publicado: (2011)

Fucoidan Derived from Undaria pinnatifida Induces Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells via the ROS-Mediated Mitochondrial Pathway
por: Yang, Lili, et al.
Publicado: (2013)

The Novel Nature Microtubule Inhibitor Ivalin Induces G2/M Arrest and Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells In Vitro
por: Liu, Fangyuan, et al.
Publicado: (2019)

Effect of berbamine on invasion and metastasis of human liver cancer SMMC-7721 cells and its possible mechanism
por: Yu, Bin-bin, et al.
Publicado: (2021)

MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells
por: Wang, Lumin, et al.
Publicado: (2013)

Synergistic Apoptotic Effect of D-Fraction From Grifola frondosa and Vitamin C on Hepatocellular Carcinoma SMMC-7721 Cells
por: Zhao, Fei, et al.
Publicado: (2016)

Recombinant VAA-I from Viscum album Induces Apoptotic Cell Death of Hepatocellular Carcinoma SMMC7721 Cells
por: Yang, Xueliang, et al.
Publicado: (2012)

Berbamine induces SMMC-7721 cell apoptosis via upregulating p53, downregulating survivin expression and activating mitochondria signaling pathway
por: Cao, Ying, et al.
Publicado: (2018)

Ethylacetate extract from Tetrastigma hemsleyanum inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells
por: Chen, Shipin, et al.
Publicado: (2018)

Psoralen inhibits malignant proliferation and induces apoptosis through triggering endoplasmic reticulum stress in human SMMC7721 hepatoma cells
por: Wang, Xiaomin, et al.
Publicado: (2019)

miR-23b inhibits proliferation of SMMC-7721 cells by directly targeting IL-11
por: Jiang, Tianpeng, et al.
Publicado: (2018)

Pure paclitaxel nanoparticles: preparation, characterization, and antitumor effect for human liver cancer SMMC-7721 cells
por: Wu, Chao, et al.
Publicado: (2018)

Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPARα and SREBP1
por: Zhang, Xiaonan, et al.
Publicado: (2019)

The Antitumor Potential of Extract of the Oak Bracket Medicinal Mushroom Inonotus baumii in SMMC-7721 Tumor Cells
por: Yang, Yue, et al.
Publicado: (2019)

Proteomics and Metabolomics Analysis Reveals the Toxicity of ZnO Quantum Dots on Human SMMC-7721 Cells
por: Yang, Yanjie, et al.
Publicado: (2023)

Chrysin inhibits sphere formation in SMMC-7721 cells via modulation of SHP-1/STAT3 signaling pathway
por: Zhang, Yanqin, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_kqdn6t98ch7nja6nbenvn3070r