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JAK/STAT3 regulated global gene expression dynamics during late-stage reprogramming process

BACKGROUND: The generation of induced pluripotent stem cells (iPSCs) has underdefined mechanisms. In addition, leukemia inhibitory factor (LIF) activated Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway is the master regulator for naïve-state pluripotency achieveme...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Jiang, Zongliang, Huang, Delun, Duan, Jingyue, Huang, Chang, Sullivan, Shannon, Vali, Kaneha, Yin, Yexuan, Zhang, Ming, Wegrzyn, Jill, Tian, Xiuchun ( Cindy), Tang, Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840728/
https://www.ncbi.nlm.nih.gov/pubmed/29510661
http://dx.doi.org/10.1186/s12864-018-4507-2