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CDK5RAP1 targeting NF-κB signaling pathway in human malignant melanoma A375 cell apoptosis

Malignant melanoma is characterized by rapid deterioration, early metastasis and high mortality. Cdk5 regulatory subunit-associated protein 1 (CDK5RAP1), which catalyzes 2-methylthio (ms(2)) modification of mitochondrial transfer RNAs, has been reported to induce cancer cell apoptosis, by a phospho-...

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Detalles Bibliográficos
Autores principales:	Xiong, Jikui, Wang, Yan, Gu, Yanli, Xue, Yadong, Dang, Lin, Li, Yuzhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840756/ https://www.ncbi.nlm.nih.gov/pubmed/29552116 http://dx.doi.org/10.3892/ol.2018.7920

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