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Safety, tolerability and efficacy of intra-articular Progenza in knee osteoarthritis: a randomized double-blind placebo-controlled single ascending dose study

BACKGROUND: Cell therapies are being investigated as potential disease modifying treatment options for osteoarthritis (OA). Progenza (PRG) comprises in vitro expanded mesenchymal stem cells derived from human donor adipose tissue combined with cell culture supernatant. The primary objective of this...

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Detalles Bibliográficos
Autores principales: Kuah, D., Sivell, S., Longworth, T., James, K., Guermazi, A., Cicuttini, F., Wang, Y., Craig, S., Comin, G., Robinson, D., Wilson, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840781/
https://www.ncbi.nlm.nih.gov/pubmed/29510712
http://dx.doi.org/10.1186/s12967-018-1420-z