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Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia

BACKGROUND: Currently, it is challenging to treat massive bone defects of proximal tibia. Although numerous methods are available for reconstruction with epiphysis preservation, limitations in knee function and complications are noted with these methods. Our paper describes our attempt to reconstruc...

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Autores principales: Lu, Minxun, Li, Yongjiang, Luo, Yi, Zhang, Wenli, Zhou, Yong, Tu, Chongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840814/
https://www.ncbi.nlm.nih.gov/pubmed/29510728
http://dx.doi.org/10.1186/s12957-018-1333-6
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author Lu, Minxun
Li, Yongjiang
Luo, Yi
Zhang, Wenli
Zhou, Yong
Tu, Chongqi
author_facet Lu, Minxun
Li, Yongjiang
Luo, Yi
Zhang, Wenli
Zhou, Yong
Tu, Chongqi
author_sort Lu, Minxun
collection PubMed
description BACKGROUND: Currently, it is challenging to treat massive bone defects of proximal tibia. Although numerous methods are available for reconstruction with epiphysis preservation, limitations in knee function and complications are noted with these methods. Our paper describes our attempt to reconstruct a marked defect in the proximal tibia with an uncemented three-dimensional (3D)-printed prosthesis and to evaluate the prosthesis design and short-term outcomes. CASE PRESENTATION: A 15-year-old boy with metaphyseal osteosarcoma of the tibia underwent intercalary allograft reconstruction following wide tumour resection with epiphysis preservation. However, chronic allograft rejection and/or infection occurred after the surgery and a sinus tract was formed. The rejection and/or infection process was successfully stopped by the removal of the graft and implantation of an antibiotic-loaded cement spacer; however, the limb function was poor. Because of the irregular shape of the defect and the excessively short length of the residual proximal tibia, we used the 3D printing technology to design and fabricate a personalised prosthesis to reconstruct the defect, with the preservation of the knee joint. At the last follow-up at 26 months, the patient had satisfactory limb function. CONCLUSIONS: The 3D-printed prosthesis may be a feasible option in the reconstruction of tibial metaphyseal defects with the preservation of the knee joint. Moreover, it can result in good postoperative function and low complication rates. However, a long-term follow-up is required to clarify its long-term outcomes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12957-018-1333-6) contains supplementary material, which is available to authorized users.
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spelling pubmed-58408142018-03-14 Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia Lu, Minxun Li, Yongjiang Luo, Yi Zhang, Wenli Zhou, Yong Tu, Chongqi World J Surg Oncol Case Report BACKGROUND: Currently, it is challenging to treat massive bone defects of proximal tibia. Although numerous methods are available for reconstruction with epiphysis preservation, limitations in knee function and complications are noted with these methods. Our paper describes our attempt to reconstruct a marked defect in the proximal tibia with an uncemented three-dimensional (3D)-printed prosthesis and to evaluate the prosthesis design and short-term outcomes. CASE PRESENTATION: A 15-year-old boy with metaphyseal osteosarcoma of the tibia underwent intercalary allograft reconstruction following wide tumour resection with epiphysis preservation. However, chronic allograft rejection and/or infection occurred after the surgery and a sinus tract was formed. The rejection and/or infection process was successfully stopped by the removal of the graft and implantation of an antibiotic-loaded cement spacer; however, the limb function was poor. Because of the irregular shape of the defect and the excessively short length of the residual proximal tibia, we used the 3D printing technology to design and fabricate a personalised prosthesis to reconstruct the defect, with the preservation of the knee joint. At the last follow-up at 26 months, the patient had satisfactory limb function. CONCLUSIONS: The 3D-printed prosthesis may be a feasible option in the reconstruction of tibial metaphyseal defects with the preservation of the knee joint. Moreover, it can result in good postoperative function and low complication rates. However, a long-term follow-up is required to clarify its long-term outcomes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12957-018-1333-6) contains supplementary material, which is available to authorized users. BioMed Central 2018-03-06 /pmc/articles/PMC5840814/ /pubmed/29510728 http://dx.doi.org/10.1186/s12957-018-1333-6 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Lu, Minxun
Li, Yongjiang
Luo, Yi
Zhang, Wenli
Zhou, Yong
Tu, Chongqi
Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title_full Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title_fullStr Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title_full_unstemmed Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title_short Uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
title_sort uncemented three-dimensional-printed prosthetic reconstruction for massive bone defects of the proximal tibia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840814/
https://www.ncbi.nlm.nih.gov/pubmed/29510728
http://dx.doi.org/10.1186/s12957-018-1333-6
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