PTEN knockdown with the Y444F mutant AAV2 vector promotes axonal regeneration in the adult optic nerve

The lack of axonal regeneration is the major cause of vision loss after optic nerve injury in adult mammals. Activating the PI3K/AKT/mTOR signaling pathway has been shown to enhance the intrinsic growth capacity of neurons and to facilitate axonal regeneration in the central nervous system after inj...

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Detalles Bibliográficos
Autores principales: Huang, Zheng-ru, Chen, Hai-ying, Hu, Zi-zhong, Xie, Ping, Liu, Qing-huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840979/
https://www.ncbi.nlm.nih.gov/pubmed/29451218
http://dx.doi.org/10.4103/1673-5374.224381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840979/
https://www.ncbi.nlm.nih.gov/pubmed/29451218
http://dx.doi.org/10.4103/1673-5374.224381

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