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The role of inhibition by phosphocitrate and its analogue in chondrocyte differentiation and subchondral bone advance in Hartley guinea pigs

Phosphocitrate (PC) and its analogue, PC-β ethyl ester, inhibit articular cartilage degeneration in Hartley guinea pigs. However, the underlying molecular mechanisms remain unclear. The present study aimed to investigate the hypothesis that PC exerted its disease-modifying effect on osteoarthritis (...

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Detalles Bibliográficos
Autores principales: Sun, Yubo, Kiraly, Alex J., Cox, Michael, Mauerhan, David R., Hanley, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841021/
https://www.ncbi.nlm.nih.gov/pubmed/29545850
http://dx.doi.org/10.3892/etm.2018.5846