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The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis
OBJECTIVE: To analyze the contralateral ear (CLE) of patients with cholesteatoma and to correlate the cholesteatoma growth pattern in the affected ear with the findings in the CLE. METHODS: Videotoscopy of both ears in 432 patients with cholesteatomas classified as posterior epitympanic (PEC), poste...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841094/ https://www.ncbi.nlm.nih.gov/pubmed/29682575 http://dx.doi.org/10.1155/2018/9817123 |
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author | Rosito, Letícia Petersen Schmidt Sperling, Neil Teixeira, Adriane Ribeiro Selaimen, Fábio André da Costa, Sady Selaimen |
author_facet | Rosito, Letícia Petersen Schmidt Sperling, Neil Teixeira, Adriane Ribeiro Selaimen, Fábio André da Costa, Sady Selaimen |
author_sort | Rosito, Letícia Petersen Schmidt |
collection | PubMed |
description | OBJECTIVE: To analyze the contralateral ear (CLE) of patients with cholesteatoma and to correlate the cholesteatoma growth pattern in the affected ear with the findings in the CLE. METHODS: Videotoscopy of both ears in 432 patients with cholesteatomas classified as posterior epitympanic (PEC), posterior mesotympanic (PMC), two routes, or undetermined. Tympanic membrane (TM) retractions were classified by location and severity and TM perforations according to signs of previous TM retraction. RESULTS: TM retraction was the most prevalent alteration in the CLE (42.6%). Cholesteatoma was observed in 17.4%. In patients with PEC, the retraction in the CLE was more frequent in the PF (66.7%) than in the PT (1.4%), and in those with two-route cholesteatoma, the retraction in the CLE most frequently involved both the PT and PF (65.6%; p < 0.0001). CONCLUSION: Our results confirm the essential role of TM retraction at least in the earlier phases of cholesteatoma pathogenesis. |
format | Online Article Text |
id | pubmed-5841094 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58410942018-04-21 The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis Rosito, Letícia Petersen Schmidt Sperling, Neil Teixeira, Adriane Ribeiro Selaimen, Fábio André da Costa, Sady Selaimen Biomed Res Int Research Article OBJECTIVE: To analyze the contralateral ear (CLE) of patients with cholesteatoma and to correlate the cholesteatoma growth pattern in the affected ear with the findings in the CLE. METHODS: Videotoscopy of both ears in 432 patients with cholesteatomas classified as posterior epitympanic (PEC), posterior mesotympanic (PMC), two routes, or undetermined. Tympanic membrane (TM) retractions were classified by location and severity and TM perforations according to signs of previous TM retraction. RESULTS: TM retraction was the most prevalent alteration in the CLE (42.6%). Cholesteatoma was observed in 17.4%. In patients with PEC, the retraction in the CLE was more frequent in the PF (66.7%) than in the PT (1.4%), and in those with two-route cholesteatoma, the retraction in the CLE most frequently involved both the PT and PF (65.6%; p < 0.0001). CONCLUSION: Our results confirm the essential role of TM retraction at least in the earlier phases of cholesteatoma pathogenesis. Hindawi 2018-02-21 /pmc/articles/PMC5841094/ /pubmed/29682575 http://dx.doi.org/10.1155/2018/9817123 Text en Copyright © 2018 Letícia Petersen Schmidt Rosito et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Rosito, Letícia Petersen Schmidt Sperling, Neil Teixeira, Adriane Ribeiro Selaimen, Fábio André da Costa, Sady Selaimen The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title | The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title_full | The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title_fullStr | The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title_full_unstemmed | The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title_short | The Role of Tympanic Membrane Retractions in Cholesteatoma Pathogenesis |
title_sort | role of tympanic membrane retractions in cholesteatoma pathogenesis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841094/ https://www.ncbi.nlm.nih.gov/pubmed/29682575 http://dx.doi.org/10.1155/2018/9817123 |
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