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IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy

Sensors of endoplasmic reticulum (ER) stress function in a co-ordinated manner. In the present study we investigated the relationship between IRE1α and PERK pathways and survival of ER stressed U937 cells and BC3 cells. To this end, we investigated the effects of a subcytotoxic concentration of Tuni...

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Detalles Bibliográficos
Autores principales:	Storniolo, Antonello, Alfano, Vincenzo, Carbotta, Sabino, Ferretti, Elisabetta, Di Renzo, Livia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841272/ https://www.ncbi.nlm.nih.gov/pubmed/29531800 http://dx.doi.org/10.1038/s41420-017-0002-9

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