Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma

Mucosal-associated invariant T (MAIT) cells are T cells that recognise vitamin-B derivative Ag presented by the MHC-related-protein 1 (MR1) antigen-presenting molecule. While MAIT cells are highly abundant in humans, their role in tumour immunity remains unknown. Here we have analysed the frequency...

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Detalles Bibliográficos
Autores principales: Gherardin, Nicholas A., Loh, Liyen, Admojo, Lorenztino, Davenport, Alexander J., Richardson, Kelden, Rogers, Amy, Darcy, Phillip K., Jenkins, Misty R., Prince, H. Miles, Harrison, Simon J., Quach, Hang, Fairlie, David P., Kedzierska, Katherine, McCluskey, James, Uldrich, Adam P., Neeson, Paul J., Ritchie, David S., Godfrey, Dale I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841305/
https://www.ncbi.nlm.nih.gov/pubmed/29515123
http://dx.doi.org/10.1038/s41598-018-22130-1

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