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Galunisertib suppresses the staminal phenotype in hepatocellular carcinoma by modulating CD44 expression

Cancer stem cells (CSCs) niche in the tumor microenvironment is responsible for cancer recurrence and therapy failure. To better understand its molecular and biological involvement in hepatocellular carcinoma (HCC) progression, one can design more effective therapies and tailored then to individual...

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Detalles Bibliográficos
Autores principales:	Rani, Bhavna, Malfettone, Andrea, Dituri, Francesco, Soukupova, Jitka, Lupo, Luigi, Mancarella, Serena, Fabregat, Isabel, Giannelli, Gianluigi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841307/ https://www.ncbi.nlm.nih.gov/pubmed/29515105 http://dx.doi.org/10.1038/s41419-018-0384-5

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