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Na(+)/Ca(2+) exchanger 1 on nuclear envelope controls PTEN/Akt pathway via nucleoplasmic Ca(2+) regulation during neuronal differentiation
Nuclear envelope (NE) is a Ca(2+)-storing organelle controlling neuronal differentiation through nuclear Ca(2+) concentrations ([Ca(2+)](n)). However, how [Ca(2+)](n) regulates this important function remains unknown. Here, we investigated the role of the nuclear form of the Na(+)/Ca(2+) exchanger 1...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841316/ https://www.ncbi.nlm.nih.gov/pubmed/29531809 http://dx.doi.org/10.1038/s41420-017-0018-1 |