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NF-κB inhibition by dimethylaminoparthenolide radiosensitizes non-small-cell lung carcinoma by blocking DNA double-strand break repair
Despite optimal chemotherapy, radiotherapy (RT), and/or surgery, non-small-cell lung carcinoma (NSCLC) remains the leading cause of cancer-related death in the US and worldwide. Thoracic RT, a mainstay in the treatment of locally advanced NSCLC, is often restricted in efficacy by a therapeutic index...
Autores principales: | Deraska, Peter V., O’Leary, Colin, Reavis, Hunter D., Labe, Shelby, Dinh, Tru-Khang, Lazaro, Jean-Bernard, Sweeney, Christopher, D’Andrea, Alan D., Kozono, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841323/ https://www.ncbi.nlm.nih.gov/pubmed/29531807 http://dx.doi.org/10.1038/s41420-017-0008-3 |
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