The convergent roles of NF-κB and ER stress in sunitinib-mediated expression of pro-tumorigenic cytokines and refractory phenotype in renal cell carcinoma

Renal cell carcinoma (RCC) is the most common form of kidney cancer. While cure remains exceptionally infrequent in RCC patients with systemic or recurrent disease, current targeted molecular strategies, including multi-targeted tyrosine kinase inhibitors (TKIs), notably changed the treatment paradi...

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Detalles Bibliográficos
Autores principales: Makhov, Peter, Naito, Sei, Haifler, Miki, Kutikov, Alexander, Boumber, Yanis, Uzzo, Robert G., Kolenko, Vladimir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841329/
https://www.ncbi.nlm.nih.gov/pubmed/29515108
http://dx.doi.org/10.1038/s41419-018-0388-1

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