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Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
BACKGROUND: Glioblastoma multiforme (GBM) is the most malignant primary tumor of the central nervous system and is associated with a very poor prognosis. No further improvements in outcomes have been reported since radiotherapy-temozolomide therapy was introduced. Therefore, developing new agents to...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841348/ https://www.ncbi.nlm.nih.gov/pubmed/29535541 http://dx.doi.org/10.2147/OTT.S155275 |