SIRT1 overexpression protects non-small cell lung cancer cells against osteopontin-induced epithelial-mesenchymal transition by suppressing NF-κB signaling

Osteopontin (OPN) is a promoter for tumor progression. It has been reported to promote non-small cell lung cancer (NSCLC) progression via the activation of nuclear factor-κB (NF-κB) signaling. As the increased acetylation of NF-κB p65 is linked to NF-κB activation, the regulation of NF-κB p65 acetyl...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xuejiao, Jiang, Zhongxiu, Li, Xiangmin, Zhang, Xiaoye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841350/
https://www.ncbi.nlm.nih.gov/pubmed/29535539
http://dx.doi.org/10.2147/OTT.S137146

Ejemplares similares

Ejemplares similares