Single-cell analyses of human islet cells reveal de-differentiation signatures

Human pancreatic islets containing insulin-secreting β-cells are notoriously heterogeneous in cell composition. Since β-cell failure is the root cause of diabetes, understanding this heterogeneity is of paramount importance. Recent reports have cataloged human islet transcriptome but not compared si...

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Detalles Bibliográficos
Autores principales: Teo, Adrian Keong Kee, Lim, Chang Siang, Cheow, Lih Feng, Kin, Tatsuya, Shapiro, James A., Kang, Nam-Young, Burkholder, William, Lau, Hwee Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841351/
https://www.ncbi.nlm.nih.gov/pubmed/29531811
http://dx.doi.org/10.1038/s41420-017-0014-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841351/
https://www.ncbi.nlm.nih.gov/pubmed/29531811
http://dx.doi.org/10.1038/s41420-017-0014-5

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