Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells

Human induced pluripotent stem cells (iPSCs) are a valuable tool for studying the cardiac developmental process in vitro, and cardiomyocytes derived from iPSCs are a putative cell source for personalized medicine. Changes in mitochondrial morphology have been shown to occur during cellular reprogram...

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Detalles Bibliográficos
Autores principales: Hoque, Ashfaqul, Sivakumaran, Priyadharshini, Bond, Simon T., Ling, Naomi X. Y., Kong, Anne M., Scott, John W., Bandara, Nadeeka, Hernández, Damián, Liu, Guei-Sheung, Wong, Raymond C. B., Ryan, Michael T., Hausenloy, Derek J., Kemp, Bruce E., Oakhill, Jonathan S., Drew, Brian G., Pébay, Alice, Lim, Shiang Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841367/
https://www.ncbi.nlm.nih.gov/pubmed/29531836
http://dx.doi.org/10.1038/s41420-018-0042-9

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