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Hybrid-denovo: a de novo OTU-picking pipeline integrating single-end and paired-end 16S sequence tags
BACKGROUND: Illumina paired-end sequencing has been increasingly popular for 16S rRNA gene-based microbiota profiling. It provides higher phylogenetic resolution than single-end reads due to a longer read length. However, the reverse read (R2) often has significant low base quality, and a large prop...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841375/ https://www.ncbi.nlm.nih.gov/pubmed/29267858 http://dx.doi.org/10.1093/gigascience/gix129 |